Anafranil 10 mg Tablet 30pcs

What Clomipramine is used for:

• Clomipramine is used to treat depression (especially if you also need to be sedated), obsessions and phobias (irrational fears).
• It is also used along with other medications to treat cataplexy.

Do not use Clomipramine :

• Are allergic to clomipramine or any of the other ingredients of this medicine
• Have ever had a rash or other allergic reaction to any other antidepressants
• Have had a heart attack within the last 3 months
• Have problems with your heart beat
• Have any serious liver disease
• Have a mental health condition called mania
• Have glaucoma (increased eye pressure)
• Have difficulty in passing urine
• Are taking, or within the last 3 weeks have taken medicines for depression called monoamine oxidase inhibitors (MAOI)
• Are taking medicines called selective, reversible monoamine oxidase-A (MAO-A) inhibitors such as moclobemide

Warnings and precautions:

• Talk to your doctor or pharmacist before taking Clomipramine if you:
• Have ever had suicidal thoughts
• Suffer from epilepsy (fits)
• Have had a head injury or have suffered brain damage
• Are going to have electric shock therapy (ECT)
• Have other problems with your heart
• Have been told you have a low level of potassium in your blood (hypokalemia)
• Have kidney disease
• Suffer from schizophrenia or other mental health conditions
• Have a blood disorder
• Have an overactive thyroid gland
• Have had severe constipation for a long time
• Have a tumor (cancer) of the adrenal gland (such as phaeochromocytoma or neuroblastoma)
• Liver disease
• Have low blood pressure
• Wear contact lenses
• Are elderly

Possible side effects:

• Stop using the product and seek immediate medical attention if you develop throat tightness or swelling of the eyes, face, lips or tongue, feel faint, or have difficulty breathing.
• Stop using the product if you develop hives or itching of the face or body.

Other medicines and Clomipramine:

• Clomipramine interacts with a large number of other medicines.
• Make sure your doctor or pharmacist knows if you are taking any of the following:
• Medicines for depression, particularly maois
• Diuretics
• Anesthetics
• Antihistamines
• Medicines for other mental health conditions such as schizophrenia or manic depression
• Medicines for high blood pressure e.g.Guanethidine, betanidine, reserpine, clonidine or alpha
• Methyldopa or norepinephrine
• Norepinephrine (noradrenaline)
• Medicines to treat heart disorders
• Beta-blockers
• Anticoagulants
• Aspirin and similar pain killing non-steroidal anti-inflammatory drugs (nsaids)
• Medicines for Parkinson's Disease
• Nicotine
• Anticonvulsants
• Decongestants
• Cimetidine
• Methylphenidate
• Rifampicin
• Quinine
• Strong painkillers such as tramadol, nefopam, morphine or morphine related substances
• Drugs of abuse including Ecstasy
• Atropine or similar medicines
• Medicines containing estrogens
• Medicines called protease inhibitors, used to treat Human Immunodeficiency Virus (HIV)
• Terbinafine
• Colestipol, cholestyramine
• John’s wort (Hypericum perforatum)
• Disulfiram
• Altretamine
• Baclofen
• Pentamidine
• Levacetylmethadol

How to use Clomipramine:

The recommended dose is:

• For depression a starting dose of 10 mg which can be increased to find a dose that works for you.
• This is normally 30 - 150 mg daily or up to a maximum of 250 mg daily for severe conditions.
• For obsessions and phobias, a starting dose of 25 mg which can be increased to 100 - 150 mg daily.
• For cataplexy a starting dose of 10 mg which can be increased to a maximum of 75 mg daily.

How to store Clomipramine :

• Store Clomipramine capsules below 25°C in a dry place.
• Keep this medicine out of the sight and reach of children.
• Do not use this medicine after the expiry date, which is stated on the pack or bottle.
• The expiry date refers to the last day of that month.
• Do not throw away any medicines via wastewater or household waste.